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[摘要]
[ 摘要 ] 目的 探讨血清雌二醇(E2)、促卵泡激素(FSH)、黄体生成素(LH)在中枢性性早熟女童诊断中的价值。 方法 选取 2020 年 1 月至 2022 年 12 月于淄博市张店区妇幼保健院就诊的 30 例中枢性性早熟女童为观察组, 并选取同期同年龄段的 30 例健康女童为对照组。比较两组血清 E2、FSH、LH 水平,并通过受试者操作特征 (ROC)曲线分析血清 E2、FSH、LH 水平对中枢性性早熟的诊断价值。 结果 观察组血清 E2、FSH、LH 水平 均高于对照组(P < 0.05)。ROC 曲线结果显示,血清 E2、FSH、LH 联合检测的曲线下面积高于单一检测 (P < 0.05)。 结论 血清 E2、FSH、LH 联合检测在中枢性性早熟女童诊断中的价值较高,临床可推广应用。
[Key word]
[Abstract]
[Abstract] Objective To investigate the value of serum estradiol (E2), follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in the diagnosis of girls with central precocious puberty. Methods From January 2020 to December 2022, 30 girls with central precocious puberty who were treated in Maternal and Child Health Hospital of Zhangdian District of Zibo City were selected as the observation group, and 30 healthy girls of the same age during the same period were selected as the control group. The serum E2, FSH and LH levels were compared between the two groups, and the diagnostic value of serum E2, FSH and LH levels in central precocious puberty was analyzed by receiver operating characteristic (ROC) curve. Results The levels of serum E2, FSH and LH in the observation group were higher than those in the control group (P < 0.05). ROC curve results showed that the combined detection of serum E2, FSH and LH had a higher area under the curve than that of single detection (P < 0.05). Conclusion The combined detection of serum E2, FSH and LH is of high value in the diagnosis of girls with central precocious puberty, and can be popularized in clinic.
[中图分类号]
R725.8
[基金项目]