[摘要]子宫内膜癌是发生于子宫内膜的上皮性恶性肿瘤，其发病率逐年递增，且发病年龄呈年轻化趋势。约75%的子宫内膜癌患者在早期发现，预后较其他妇科恶性肿瘤好。手术是绝大多数子宫内膜癌患者的主要治疗方法，对于临床早期低级别子宫内膜癌患者，预后普遍良好，仅手术治疗就可达到临床治愈。但对于早期子宫内膜癌能否保留卵巢存有争议。本文将对早期子宫内膜癌保留卵巢的现状及争议进行阐述，并从肿瘤学角度和内分泌学角度探讨早期子宫内膜癌保留卵巢的利弊。

[Abstract] Endometrial carcinoma is an epithelial malignant tumor occurring in the endometrial. Its incidence increases year by year, and the onset age is trending younger. About 75% of endometrial carcinoma patients are detected at early stage and have better prognosis than other gynecological malignancies. Surgery is the main treatment for most of the patients with endometrial carcinoma. For patients with low-grade endometrial carcinoma in early stage,the prognosis is generally good, and clinical cure can be achieved with surgery alone. However, there are controversies about whether ovaries can be preserved in early-stage endometrial carcinoma. This article will elaborate the current situation and controversies of preserving ovaries in early endometrial carcinoma, and discuss the advantages and disadvantages of preserving ovaries in early endometrial carcinoma from oncological and endocrinological perspectives.

R737.3

河北省医学科学研究课题计划（20190208）